Target General Information
Target ID T10191
Target Name T-cell surface glycoprotein CD4
Synonyms T-cell surface antigen T4/Leu-3; CD4
Target Type Clinical Trial
Gene Name CD4
Biochemical Class Immunoglobulin
UniProt ID CD4_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 546305Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007359)
Ref 533077A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway. Immunol Cell Biol. 2015 Apr;93(4):396-405.
Ref 522956ClinicalTrials.gov (NCT01072383) Safety and Efficacy of Multiple Doses of BT061 in Patients With Moderate to Severe Chronic Plaque Psoriasis. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.