Target General Information
Target ID T10965
Target Name P-selectin
Synonyms CD62P; GMP-140; Granule membrane protein 140; LECAM3; Leukocyte-endothelial cell adhesion molecule 3; PADGEM; SELP
Target Type Clinical Trial
Gene Name SELP
Biochemical Class Selectin/LECAM
UniProt ID LYAM3_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 543059(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8307).
Ref 530945GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice. Blood. 2010 Sep 9;116(10):1779-86.
Ref 531721Deal watch: Pfizer deal for selectin inhibitor highlights potential of glycomimetic drugs. Nat Rev Drug Discov. 2011 Dec 1;10(12):890.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.