Target General Information
Target ID T17758
Target Name Urokinase-type plasminogen activator
Synonyms U-plasminogen activator; UPA; PLAU
Target Type Successful
Gene Name PLAU
Biochemical Class Peptidase
UniProt ID UROK_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 541632(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6497).
Ref 532234Phase II randomised proof-of-concept study of the urokinase inhibitor upamostat (WX-671) in combination with gemcitabine compared with gemcitabine alone in patients with non-resectable, locally advanced pancreatic cancer. Br J Cancer. 2013 Mar 5;108(4):766-70.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.