Target General Information
Target ID T18779
Target Name Mucin 1
Synonyms Breast carcinoma-associated antigen DF3; CD227 antigen; Carcinoma-associated mucin; EMA; Episialin; H23AG; MUC-1; PEM; PEMT; PUM; Peanut-reactive urinary mucin; Polymorphic epithelial mucin; Tumor-associated epithelial membraneantigen; Tumor-associated mucin; Tumour-associated antigen mucin 1; MUC1
Target Type Clinical Trial
Gene Name MUC1
Biochemical Class Transmembrane protein
UniProt ID MUC1_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref
Ref 529572A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV Non-small cell lung cancer. J Thorac Oncol. 2008 Jul;3(7):735-44.
Ref 530436Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer. Breast Cancer Res. 2009;11(5):R73.
Ref 522466ClinicalTrials.gov (NCT00773097) Study of the MUC1 Peptide-Poly-ICLC Adjuvant Vaccine in Individuals With Advanced Colorectal Adenoma. U.S. National Institutes of Health.
Ref 522556ClinicalTrials.gov (NCT00828009) BLP25 Liposome Vaccine and Bevacizumab After Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Stage IIIA or Stage IIIB Non-Small Cell LungCancer That Cannot Be Removed by Surgery. U.S. National Institutes of Health.
Ref 523236ClinicalTrials.gov (NCT01232712) A Study to Assess the Safety and Efficacy of MUC1 Peptide Vaccine and hGM-CSF in Patients With MUC1-positive Tumor Malignancies. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.