Target General Information
Target ID T22095
Target Name Interleukin-17
Synonyms CTLA-8; Cytotoxic T lymphocyte-associated antigen 8; IL-17; IL-17A; IL17A
Target Type Successful
Gene Name IL17B
Biochemical Class Cytokine: interleukin
UniProt ID IL17B_HUMAN||IL17C_HUMAN||IL17D_HUMAN||IL17F_HUMAN||IL17_HUMAN||IL25_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 525076ClinicalTrials.gov (NCT02349451) A Phase 2 Study to Investigate the Safety, Tolerability and Efficacy of ABT-122 in Subjects With Active Psoriatic Arthritis Who Have an Inadequate Response to Methotrexate. U.S. National Institutes of Health.
Ref 889413ClinicalTrials.gov (NCT02433340) Phase 2, Multicenter, Open-Label Extension (OLE) Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.