Target expression details

Target General Information
Target ID T24587
Target Name O-6-methylguanine-DNA-alkyltransferase
Synonyms 6-O-methylguanine-DNA methyltransferase; Human O(6)-alkylguanine-DNA alkyltransferase; O-6-methylguanine-DNA-alkyltransferase; MGMT
Target Type Clinical Trial
Gene Name MGMT
Biochemical Class Methyltransferase superfamily
UniProt ID MGMT_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 527774Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol. 2005 Oct 1;23(28):7178-87.
Ref 529958Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. J Clin Oncol. 2009 Mar 10;27(8):1262-7.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.