Target General Information
Target ID T24982
Target Name Ileal sodium/bile acid cotransporter
Synonyms ASBT; Apical sodiumdependent bile acid transporter; IBAT; ISBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium/bile acid cotransporter; Ileal sodiumdependent bile acid transporter; Na(+)dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2; SLC10A2
Target Type Clinical Trial
Gene Name SLC10A2
Biochemical Class Bile acid:na(+) symporter
UniProt ID NTCP2_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 532355Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. J Med Chem. 2013 Jun 27;56(12):5094-114.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.