Target General Information
Target ID T26500
Target Name Histamine H4 receptor
Synonyms AXOR35; G protein-coupled receptor 105; GPCR105; GPRv53; H4 receptor; HH4R; SP9144; HRH4
Target Type Clinical Trial
Gene Name HRH4
Biochemical Class GPCR rhodopsin
UniProt ID HRH4_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 531625Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.
Ref 525005ClinicalTrials.gov (NCT02295865) A Study to Evaluate Safety and Efficacy of Toreforant (JNJ-38518168) in Participants With Moderate to Severe Plaque-type Psoriasis. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.