Target General Information
Target ID T27325
Target Name Human DNA topoisomerase I
Synonyms Topoisomerase-I; TOP1MT
Target Type Successful
Gene Name TOP1
Biochemical Class DNA topoisomerase
UniProt ID TOP1_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref
Ref 544836Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001278)
Ref 538552FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020671.
Ref 541905(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6823).
Ref 542109(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7101).
Ref 535668New drugs for the treatment of cancer, 1990-2001. Isr Med Assoc J. 2002 Dec;4(12):1124-31.
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.