Target General Information
Target ID T53389
Target Name TGF-beta receptor type I
Synonyms ALK-5; Activin receptor-like kinase 5; SKR4; Serine/threonine-protein kinase receptor R4; TGF-beta type I receptor; TGFR-1; TbetaRI; Type I TGFbeta receptor kinase; TGFBR1
Target Type Clinical Trial
Gene Name TGFBR1
Biochemical Class Kinase
UniProt ID TGFR1_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 547088Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012957)
Ref 542748(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7797).
Ref 524562ClinicalTrials.gov (NCT02008318) A Study of LY2157299 in Participants With Myelodysplastic Syndromes. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.