Target expression details

Target General Information
Target ID T59102
Target Name PDGF receptor beta
Synonyms Beta-PDGFR; CD140b antigen; PDGF-R-beta; Platelet-derived growth factor receptor beta; PDGFRB
Target Type Successful
Gene Name PDGFRB
Biochemical Class Kinase
UniProt ID PGFRB_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref
Ref 541050(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5711).
Ref 528230Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature. Methods Enzymol. 2006;407:597-612.
Ref 530708MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor. Cancer Res. 2010 Feb 15;70(4):1524-33.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.