Target General Information
Target ID T59881
Target Name Vasopressin V1b receptor
Synonyms AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; V1bR; Vasopressin V(1b) Receptor; Vasopressin V3 receptor; AVPR1B
Target Type Successful
Gene Name AVPR1B
Biochemical Class GPCR rhodopsin
UniProt ID V1BR_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 539402(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2202).
Ref 535432Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6370-5. Epub 2002 Apr 16.
Ref 536580Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug;33(9):2080-92. Epub 2008 Jan 2.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.