Target General Information
Target ID T69912
Target Name Platelet-activating factor acetylhydrolase
Synonyms 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; LDL-PLA(2); LDL-associated phospholipase A2; Lipoprotein-associated phospholipase A2; PAF 2-acylhydrolase; PAF acetylhydrolase; PLA2G7
Target Type Clinical Trial
Gene Name PLA2G7
Biochemical Class Carboxylic ester hydrolase
UniProt ID PAFA_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 547940Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020582)
Ref 521515ClinicalTrials.gov (NCT00037687) Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis. U.S. National Institutes of Health.
Ref 524402ClinicalTrials.gov (NCT01924858) A Positron Emission Tomography (PET) Study to Investigate the Brain Biodistribution of 18F GSK2647544 in Healthy Subjects to Determine Its Ability to Cross the Blood-brain-barrier.. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.