Target General Information
Target ID T78356
Target Name Thromboxane-A synthase
Synonyms TS; TXA synthase; TXS; Thromboxane A2 synthase; TBXAS1
Target Type Clinical Trial
Gene Name TBXAS1
Biochemical Class Intramolecular oxidoreductases
UniProt ID THAS_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 534187Structure-activity relationships of (E)-3-(1,4-benzoquinonyl)-2-[(3-pyridyl)-alkyl]-2-propenoic acid derivatives that inhibit both 5-lipoxygenase and thromboxane A2 synthetase. J Med Chem. 1996 Aug 2;39(16):3148-57.
Ref 523832ClinicalTrials.gov (NCT01551381) Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EV-077 in Type 2 Diabetic Subjects. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.