Target General Information
Target ID T78429
Target Name Inhibitor of nuclear factor kappa B kinase beta
Synonyms I-kappa-B kinase 2; I-kappa-B-kinase beta; IKK-2; IKK-B; IKK-beta; IKK2; IKKbeta; IkBKB; IkappaB kinase 2; IkappaB kinase beta; Inhibitory kappa B kinase b; NFKBIKB; Nuclear factor NF-kappa-B inhibitor kinase beta; IKBKB
Target Type Clinical Trial
Gene Name IKBKB
Biochemical Class Kinase
UniProt ID IKKB_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref
Ref 532068Inhibition of I?B phosphorylation prevents load-induced cardiac dysfunction in mice. Am J Physiol Heart Circ Physiol. 2012 Dec 15;303(12):H1435-45.
Ref 523903ClinicalTrials.gov (NCT01598415) Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part II. U.S. National Institutes ofHealth.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.