Target General Information
Target ID T80896
Target Name Estrogen receptor beta
Synonyms Beta-1; ER-beta; Erbeta; Oestrogen receptor beta; ESR2
Target Type Successful
Gene Name ESR2
Biochemical Class Nuclear hormone receptor
UniProt ID ESR2_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 549961Clinical pipeline report, company report or official report of Lilly.
Ref 539868(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2826).
Ref 536772New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202.
Ref 521695ClinicalTrials.gov (NCT00190697) A Study of LY353381 (Arzoxifene) for Patients Who Benefitted From This Drug in Other Oncology Trials and Wished to Continue Treatment. U.S. National Institutes of Health.
Ref 522385ClinicalTrials.gov (NCT00722202) Study Evaluating the Safety and Pharmacokinetics (PK) of Ascending Single IV Doses of ERB-257 in Healthy Japanese Males. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.