Target General Information
Target ID T83011
Target Name Monoamine oxidase type B
Synonyms MAO-B; Monoamine oxidase; Monoamine oxidase B; MAOB
Target Type Successful
Gene Name MAOB
Biochemical Class Oxidoreductases acting on CH-NH2 group of donors
UniProt ID AOFB_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 538452FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 011909.
Ref 539613(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2489).
Ref 542285(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7266).
Ref 531772Ladostigil: a novel multimodal neuroprotective drug with cholinesterase and brain-selective monoamine oxidase inhibitory activities for Alzheimer's disease treatment. Curr Drug Targets. 2012 Apr;13(4):483-94.
Ref 523529ClinicalTrials.gov (NCT01383694) Effect Of Piperine In Patients With Oropharyngeal Dysphagia. U.S. National Institutes of Health.
Ref 889446Drugs@FDA (Edaravone)
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.