Target General Information
Target ID T85799
Target Name Cyclin-dependent kinase 4
Synonyms Cyclin-dependent kinase 4; PSK-J3; CDK4
Target Type Successful
Gene Name CDK4
Biochemical Class Kinase
UniProt ID CDK4_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref
Ref 542800(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7874).
Ref 531973BAY 1000394, a novel cyclin-dependent kinase inhibitor, with potent antitumor activity in mono- and in combination treatment upon oral application. Mol Cancer Ther. 2012 Oct;11(10):2265-73.
Ref 889446Drugs@FDA (Edaravone)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.