Target General Information
Target ID T87675
Target Name Aurora kinase A
Synonyms Aurora-A; Aurora-related kinase 1; Aurora/IPL1-related kinase 1; Breast tumor-amplified kinase; Serine/threonine kinase 15; Serine/threonine-protein kinase 6; hARK1; AURKA
Target Type Clinical Trial
Gene Name AURKA||Synonyms=AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6
Biochemical Class Kinase
UniProt ID AURKA_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 548410Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025382)
Ref 542810(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7885).
Ref 542852(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7937).
Ref 531311ENMD-2076 is an orally active kinase inhibitor with antiangiogenic and antiproliferative mechanisms of action. Mol Cancer Ther. 2011 Jan;10(1):126-37.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.