Target Information

Target General Infomation
Target ID
T33902
Former ID
TTDI03234
Target Name
GPR17
Gene Name
GPR17
Synonyms
GPR17
Target Type
Research
UniProt ID
Q13304
Sequence
MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENM
LFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHF
SGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLAC
AFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCY
LLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQ
RILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESS
LSAKSEL
Agonist ASN02563583 Drug Info [531551]
ASN04421891 Drug Info [531551]
ASN04450772 Drug Info [531551]
ASN04885796 Drug Info [531551]
ASN06917370 Drug Info [531551]
LTC4 Drug Info [528446]
LTD4 Drug Info [528446]
LTE4 Drug Info [529783]
UDP-glucose Drug Info [528446]
References
Ref 528446The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. EMBO J. 2006 Oct 4;25(19):4615-27. Epub 2006 Sep 21.
Ref 529783The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One. 2008;3(10):e3579.
Ref 531551In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases. J Comput Aided Mol Des. 2011 Aug;25(8):743-52.