Details of Disease | DrugMAP

General Information of Disease (ID: DIS0QP8G)

Disease Name	Atrial conduction disease
Synonyms	CARDIAC conduction disease with or without dilated cardiomyopathy; familial atrial tachyarrhythmia-infra-Hisian cardiac conduction disease; CCDD
Definition	Atrial conduction disorder is a form of heart disease in which the conduction of the cardiac atrium is disrupted.
Disease Hierarchy	DISMT2VZ: Cardiogenetic disease DISED5HG: Conduction system disorder DIS0QP8G: Atrial conduction disease
Disease Identifiers	MONDO ID MONDO_0014500 UMLS CUI C4015285 OMIM ID 616117 MedGen ID 863722 Orphanet ID 436242

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
COL25A1	OT7M23Z9	Strong	Biomarker	[1]
TNNI3K	OTJ6CWUN	Strong	Autosomal dominant	[2]
------------------------------------------------------------------------------------

References

1	Recessive mutations in COL25A1 are a cause of congenital cranial dysinnervation disorder. Am J Hum Genet. 2015 Jan 8;96(1):147-52. doi: 10.1016/j.ajhg.2014.11.006. Epub 2014 Dec 11.
2	The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.