Details of Disease | DrugMAP

General Information of Disease (ID: DIS1AYEJ)

Disease Name	Familial Mediterranean fever, autosomal dominant
Synonyms	Fmf, autosomal dominant; familial Mediterranean fever, autosomal dominant; familial Mediterranean fever, AD
Disease Hierarchy	DISVP5WP: Familial Mediterranean fever DIS1AYEJ: Familial Mediterranean fever, autosomal dominant
Disease Identifiers	MONDO ID MONDO_0007601 MESH ID D010505 UMLS CUI C1851347 OMIM ID 134610 MedGen ID 341987

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
MEFV	OTRJ6S6K	Strong	Autosomal recessive	[1]
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References

1	Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol Cell. 2003 Mar;11(3):591-604. doi: 10.1016/s1097-2765(03)00056-x.