General Information of Disease (ID: DIS22GGG)

Disease Name Vibratory urticaria
Definition
This very rare form of angioedema develops in reply to contact with vibration. In vibratory angioedema, symptoms develop within two to five minutes after contact with vibration and dissolve after about an hour. Patients with this disorder do not suffer from dermographism or pressure urticaria. Vibratory angioedema is diagnosed by holding a vibrating device such as a laboratory vortex machine against the forearm for four minutes. Speedy swelling of the whole forearm extending into the upper arm is also noted later. The principal treatment is avoidance of vibratory stimulants. Antihistamines have also been proven helpful.|Editor note: TODO add ECTO
Disease Hierarchy
:
DIS22GGG: Vibratory urticaria
Disease Identifiers
MONDO ID
MONDO_0006618
MESH ID
D000094482
UMLS CUI
C0157743
OMIM ID
125630
MedGen ID
510413
HPO ID
HP:0410138
SNOMED CT ID
51247001

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ADGRE2 OTUYJVYG Strong Genetic Variation [1]
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References

1 Mast cells signal their importance in health and disease.J Allergy Clin Immunol. 2018 Aug;142(2):381-393. doi: 10.1016/j.jaci.2018.01.034. Epub 2018 Feb 15.