Details of Disease | DrugMAP

General Information of Disease (ID: DIS2QZI9)

Disease Name	Autosomal recessive spastic paraplegia type 59
Synonyms	SPG59
Disease Hierarchy	DIS9KXQY: Complex hereditary spastic paraplegia DIS2QZI9: Autosomal recessive spastic paraplegia type 59
Disease Identifiers	MONDO ID MONDO_0018416 UMLS CUI C4750857 MedGen ID 1669596 Orphanet ID 401795 SNOMED CT ID 773425000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
USP8	OTOXC2IP	Supportive	Autosomal recessive	[1]
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This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
USP8	TT1J07C	Supportive	Autosomal recessive	[1]
USP8	TT1J07C	Strong	GermlineCausalMutation	[1]
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References

1	Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders. Science. 2014 Jan 31;343(6170):506-511. doi: 10.1126/science.1247363.