Details of Disease | DrugMAP

General Information of Disease (ID: DIS33XI0)

Disease Name	Autosomal dominant nonsyndromic hearing loss 36
Synonyms	deafness, autosomal dominant 36; TMC1 autosomal dominant nonsyndromic deafness; autosomal dominant nonsyndromic deafness caused by mutation in TMC1; autosomal dominant nonsyndromic deafness type 36; autosomal dominant nonsyndromic deafness 36; autosomal dominant deafness 36; DFNA36; deafness, autosomal dominant type 36
Definition	Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the TMC1 gene.
Disease Hierarchy	DISYC1G0: Autosomal dominant nonsyndromic hearing loss DIS33XI0: Autosomal dominant nonsyndromic hearing loss 36
Disease Identifiers	MONDO ID MONDO_0011708 MESH ID C564675 UMLS CUI C1847626 OMIM ID 606705 MedGen ID 376173

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
TMC1	OTHYH8MU	Strong	Autosomal dominant	[1]
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References

1	Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function. Nat Genet. 2002 Mar;30(3):277-84. doi: 10.1038/ng842. Epub 2002 Feb 19.