Details of Disease | DrugMAP

General Information of Disease (ID: DIS3YK8P)

Disease Name	Cortical dysplasia, complex, with other brain malformations 10
Synonyms	CDCBM10; CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 10
Disease Hierarchy	DISTLV37: Complex cortical dysplasia with other brain malformations DIS3YK8P: Cortical dysplasia, complex, with other brain malformations 10
Disease Identifiers	MONDO ID MONDO_0032866 UMLS CUI C5231458 OMIM ID 618677 MedGen ID 1684859

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
APC2	TTSMK36	Strong	Autosomal recessive	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
APC2	OTRH91CX	Strong	Autosomal recessive	[1]
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References

1	Bi-allelic Loss of Human APC2, Encoding Adenomatous Polyposis Coli Protein 2, Leads to Lissencephaly, Subcortical Heterotopia, and Global Developmental Delay. Am J Hum Genet. 2019 Oct 3;105(4):844-853. doi: 10.1016/j.ajhg.2019.08.013.