Details of Disease | DrugMAP

General Information of Disease (ID: DIS4PPKA)

Disease Name	Specific language impairment 5
Synonyms	specific language impairment 5; SLI5; specific language impairment type 5
Definition	A communication disorder that involves the processing of linguistic information.
Disease Hierarchy	DISEKRML: Specific language impairment DIS4PPKA: Specific language impairment 5
Disease Identifiers	MONDO ID MONDO_0014184 UMLS CUI C3809483 OMIM ID 615432 MedGen ID 815813

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
TM4SF20	OTNXU9QW	Limited	Autosomal dominant	[1]
NOP9	OTA3O9QW	Strong	Genetic Variation	[2]
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References

1	TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet. 2013 Aug 8;93(2):197-210. doi: 10.1016/j.ajhg.2013.05.027. Epub 2013 Jun 27.
2	Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment.Genes Brain Behav. 2014 Apr;13(4):418-29. doi: 10.1111/gbb.12127. Epub 2014 Mar 24.