Details of Disease

General Information of Disease (ID: DIS5VDG3)

Disease Name Candidiasis, invasive
Synonyms invasive candidiases; candidiases, invasive; invasive candidiasis
Definition A fungal infection by any of the Candida species in a sterile body compartment.
Disease Hierarchy
DISIRYMU: Candidiasis
DIS5VDG3: Candidiasis, invasive
Disease Identifiers
MONDO ID
MONDO_0044067
MESH ID
D058365
UMLS CUI
C1609535
MedGen ID
296300

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 7 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
CARD9 OTJ81AWD Strong Biomarker [1]
CD101 OT4QX6BR Strong Biomarker [2]
DBF4 OTBL7JHQ Strong Biomarker [3]
FXYD4 OT06IH3H Strong Biomarker [3]
IFIT2 OTI4EOAR Strong Biomarker [4]
LRRCC1 OTVEBJ1V Strong Biomarker [5]
SETD1A OTVVWRIC Strong Biomarker [6]
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⏷ Show the Full List of 7 DOT(s)

References

1 A 7-Year-Old Child With Headaches and Prolonged Fever Associated With Oral and Nail Lesions.Open Forum Infect Dis. 2019 Nov 3;6(11):ofz229. doi: 10.1093/ofid/ofz229. eCollection 2019 Nov.
2 Population Pharmacokinetic Analyses for Rezafungin (CD101) Efficacy Using Phase 1 Data.Antimicrob Agents Chemother. 2018 May 25;62(6):e02603-17. doi: 10.1128/AAC.02603-17. Print 2018 Jun.
3 Five-Year National Surveillance of Invasive Candidiasis: Species Distribution and Azole Susceptibility from the China Hospital Invasive Fungal Surveillance Net (CHIF-NET) Study.J Clin Microbiol. 2018 Jun 25;56(7):e00577-18. doi: 10.1128/JCM.00577-18. Print 2018 Jul.
4 Pathogenic Effects of IFIT2 and Interferon- during Fatal Systemic Candida albicans Infection.mBio. 2018 Apr 17;9(2):e00365-18. doi: 10.1128/mBio.00365-18.
5 The use of hybrid phage displaying antigen epitope and recombinant protein in the diagnosis of systemic Candida albicans infection in rabbits and cancer patients.Diagn Microbiol Infect Dis. 2010 Dec;68(4):382-9. doi: 10.1016/j.diagmicrobio.2010.07.009. Epub 2010 Sep 29.
6 Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis.Mol Microbiol. 2006 May;60(3):697-709. doi: 10.1111/j.1365-2958.2006.05121.x.