Details of Disease | DrugMAP

General Information of Disease (ID: DIS68KSY)

Disease Name	Dilated cardiomyopathy 1NN
Synonyms	cardiomyopathy, dilated, 1NN; familial isolated dilated cardiomyopathy caused by mutation in RAF1; dilated cardiomyopathy type 1NN; RAF1 familial isolated dilated cardiomyopathy; cardiomyopathy, dilated, type 1Nn; CMD1NN
Definition	Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the RAF1 gene.
Disease Hierarchy	DISBHDU9: Familial dilated cardiomyopathy DIS68KSY: Dilated cardiomyopathy 1NN
Disease Identifiers	MONDO ID MONDO_0014396 UMLS CUI C4014656 OMIM ID 615916 MedGen ID 863093

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
RAF1	TTB18GJ	Strong	Autosomal dominant	[1]
RAF1	TTAN5W2	Strong	Genetic Variation	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
RAF1	OT51LSFO	Strong	Autosomal dominant	[1]
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References

1	RAF1 mutations in childhood-onset dilated cardiomyopathy. Nat Genet. 2014 Jun;46(6):635-639. doi: 10.1038/ng.2963. Epub 2014 Apr 28.