Details of Disease | DrugMAP

General Information of Disease (ID: DIS6DJ2Y)

Disease Name	Meester-Loeys syndrome
Synonyms	Meester-Loeys syndrome; Meester-Loeys syndrome; MRLS; MRLS
Disease Hierarchy	DIS6SVEE: Syndromic disease DISYKSRF: Genetic disease DIS6DJ2Y: Meester-Loeys syndrome
Disease Identifiers	MONDO ID MONDO_0010515 UMLS CUI C4310811 OMIM ID 300989 MedGen ID 934778

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
BGN	TT0JPVF	Strong	X-linked	[1]
BGN	TT0JPVF	Strong	Genetic Variation	[2]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
BGN	OT3AV6IF	Strong	X-linked	[1]
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References

1	The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.
2	Loss-of-function mutations in the X-linked biglycan gene cause a severe syndromic form of thoracic aortic aneurysms and dissections. Genet Med. 2017 Apr;19(4):386-395. doi: 10.1038/gim.2016.126. Epub 2016 Sep 15.