Details of Disease

General Information of Disease (ID: DIS6R3ML)

• Disease Name: Heart transplant rejection
• Disease Class: NE84: Transplant rejection
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DIS6R3ML: Heart transplant rejection
• ICD Code:
  ICD-11: ICD-11: NE84
  ICD-9: ICD-9: 996
  Expand ICD-9: 996

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Belatacept	DMXLYQF	Approved	NA	[1]

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Inolimomab	DMUS1F8	Phase 3	Monoclonal antibody	[2]
Ortataxel	DM1EK5D	Phase 2	Small molecular drug	[2]

This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
BXL-01-0029	DM105FT	Investigative	NA	[3]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6892).
• [2] New developments in immunosuppressive therapy for heart transplantation. Expert Opin Emerg Drugs. 2009 Mar;14(1):1-21.
• [3] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.