Details of Disease | DrugMAP

General Information of Disease (ID: DIS8TX4M)

Disease Name	Cleft palate, proliferative retinopathy, and developmental delay
Synonyms	CPPRDD
Disease Hierarchy	DISYKSRF: Genetic disease DIS8TX4M: Cleft palate, proliferative retinopathy, and developmental delay
Disease Identifiers	MONDO ID MONDO_0033641 UMLS CUI C5436739 OMIM ID 619074 MedGen ID 1765503

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
LRRC32	TT0FAYT	Strong	Autosomal recessive	[1]
------------------------------------------------------------------------------------

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
LRRC32	OTG7EDZL	Strong	Autosomal recessive	[1]
------------------------------------------------------------------------------------

References

1	Glycoprotein A repetitions predominant (GARP) positively regulates transforming growth factor (TGF) 3 and is essential for mouse palatogenesis. J Biol Chem. 2017 Nov 3;292(44):18091-18097. doi: 10.1074/jbc.M117.797613. Epub 2017 Sep 14.