Details of Disease

General Information of Disease (ID: DIS8XLC5)

• Disease Name: Heavy metal poisoning
• Synonyms: chronic heavy metal poisoning; heavy metal toxicosis; heavy metal toxicity; toxic effect of heavy metal; heavy metal poisoning
• Disease Class: NE60: Drugs/medicaments/biological substances harmful effect
• Definition: Heavy metal poisoning refers to when excessive exposure to a heavy metal affects the normal function of the body. Examples of heavy metals that can cause toxicity include lead, mercury, arsenic, cadmium, and chromium. Exposure may occur through the diet, from medications, from the environment, or in the course of work or play. Heavy metals can enter the body through the skin, or by inhalation or ingestion. Toxicity can result from sudden, severe exposure, or from chronic exposure over time. Symptoms can vary depending on the metal involved, the amount absorbed, and the age of the person exposed. For example, young children are more susceptible to the effects of lead exposure because they absorb more compared with adults and their brains are still developing. Nausea, vomiting, diarrhea, and abdominal pain are common symptoms of acute metal ingestion. Chronic exposure may cause various symptoms resulting from damage to body organs, and may increase the risk of cancer. Treatment depends on the circumstances of the exposure.
• Disease Hierarchy:
  DIS7OPRV: Intoxication
  DIS8XLC5: Heavy metal poisoning
• ICD Code:
  ICD-11: ICD-11: NE60
  ICD-10: ICD-10: X49

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
ATON-004	DMVJ9KO	Discontinued in Phase 2	NA	[1]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032208)