Details of Disease | DrugMAP

General Information of Disease (ID: DIS99333)

Disease Name	Classic or attenuated familial adenomatous polyposis
Synonyms	classic or attenuated familial adenomatous polyposis; classic or attenuated FAP
Definition	An inherited diseases haracterized by the development of adenomas in the rectum and colon; classified into classic FAP and attenuated FAP.
Disease Hierarchy	DISFZFI4: Intestinal polyposis syndrome DIS99333: Classic or attenuated familial adenomatous polyposis

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
APC	OTKV0TIK	Definitive	Autosomal dominant	[1]
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References

1	Technical standards for the interpretation and reporting of constitutional copy-number variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics (ACMG) and the Clinical Genome Resource (ClinGen). Genet Med. 2020 Feb;22(2):245-257. doi: 10.1038/s41436-019-0686-8. Epub 2019 Nov 6.