Details of Disease | DrugMAP

General Information of Disease (ID: DISA748M)

Disease Name	Obsolete hypoplastic tibiae-postaxial polydactyly syndrome
Disease Hierarchy	DIS01GPL: Grass pollen hypersensitivity DISA748M: Obsolete hypoplastic tibiae-postaxial polydactyly syndrome

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
SHH	TTIENCJ	Supportive	Autosomal dominant	[1]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
LMBR1	OTGRQK9V	Supportive	Autosomal dominant	[1]
SHH	OTOG2BXF	Supportive	Autosomal dominant	[1]
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References

1	A specific mutation in the distant sonic hedgehog (SHH) cis-regulator (ZRS) causes Werner mesomelic syndrome (WMS) while complete ZRS duplications underlie Haas type polysyndactyly and preaxial polydactyly (PPD) with or without triphalangeal thumb. Hum Mutat. 2010 Jan;31(1):81-9. doi: 10.1002/humu.21142.