Details of Disease

General Information of Disease (ID: DISBHR1G)

• Disease Name: Athylene glycol or methanol poisoning
• Disease Class: NE61: Eexposure to noxious substances harmful effect
• Definition: Ethylene glycol poisoning is a rare poisoning resulting in elevated anion gap metabolic acidosis, due to the production of glycolic acid, glyoxylic acid, and oxalic acid by alcohol dehydrogenase (ADH) in the liver when ethylene glycol is metabolized, characterized initially by euphoria, slurred speech, encephalopathy, coma and seizures, and followed by late manifestations such as tachycardia, arrhythmias, myocardial depression, hemodynamic imbalance and, finally, acute renal failure.
• Disease Hierarchy:
  DIS7OPRV: Intoxication
  DISBHR1G: Athylene glycol or methanol poisoning
• ICD Code:
  ICD-11: ICD-11: NE61
  ICD-10: ICD-10: T51.1, T52.3
  ICD-9: ICD-9: 980.1, 982
  Expand ICD-9: 980.1,982

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Fomepizole	DM6VOWQ	Approved	Small molecular drug	[1]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.