Details of Disease

General Information of Disease (ID: DISBO2ZC)

Disease Name Vesicoureteral reflux 2
Synonyms VUR2; vesicoureteral reflux 2; vesicoureteral reflux (disease) caused by mutation in ROBO2; vesicoureteral reflux type 2; ROBO2 vesicoureteral reflux (disease)
Definition Any vesicoureteral reflux in which the cause of the disease is a mutation in the ROBO2 gene.
Disease Hierarchy
DISUME5E: Familial vesicoureteral reflux
DISBO2ZC: Vesicoureteral reflux 2
Disease Identifiers
MONDO ID
MONDO_0012573
MESH ID
C567053
UMLS CUI
C1970483
OMIM ID
610878
MedGen ID
370270

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ROBO2 OTFJ9FQW Strong Autosomal dominant [1]
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References

1 Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.