General Information of Disease (ID: DISCA0OX)

Disease Name Horizontal gaze palsy with progressive scoliosis
Synonyms
gaze palsy, familial horizontal, with progressive scoliosis; gaze palsy, horizontal, with progressive scoliosis; ophthalmoplegia, progressive external, and scoliosis; progressive external ophthalmoplegia and scoliosis; HGPPS
Definition
Horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare congenital autosomal recessive disease, presenting in children and adolescents, and characterized by progressive scoliosis along with the absence of conjugate horizontal eye movements and associated with failure of the somatosensory and corticospinal neuronal tracts to decussate in the medulla.
Disease Hierarchy
DISQCXZX: Disorder of development or morphogenesis
DISYKSRF: Genetic disease
DISCA0OX: Horizontal gaze palsy with progressive scoliosis
Disease Identifiers
MONDO ID
MONDO_0011810
MESH ID
C564593
UMLS CUI
C4760875
MedGen ID
1683615
Orphanet ID
2744