Details of Disease
General Information of Disease (ID: DISDDZ65)
| Disease Name | ACTH-independent Cushing syndrome | ||||
|---|---|---|---|---|---|
| Synonyms | corticotropin-independent Cushing syndrome; adrenocorticotropic hormone-independent Cushing syndrome; adrenal Cushing syndrome | ||||
| Definition |
Adrenocorticotropic hormone (ACTH) independent Cushing syndrome is a form of endogenous Cushing syndrome (CS) that may result from excess secretion of cortisol by either a unilateral and benign (adrenocortical adenoma: 55-60%) or malignant (adrenocortical carcinoma: 35-40 %) adrenocortical tumor or by bilateral adrenal secretion by macronodular adrenal hyperplasia (AIMAH), as an isolated disease or as part of McCune-Albright syndrome (MAS), or by primary pigmented nodular adrenocortical disease (PPNAD), as an isolated disease or as part of Carney complex (CNC).
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