Details of Disease

General Information of Disease (ID: DISE0HPX)

Disease Name Morton neuroma
Synonyms interdigital nerve compression syndrome; intermetatarsal neuroma; interdigital neuroma; Morton entrapment; interdigital neuritis; Morton metatarsalgia; interdigital neuralgia
Disease Class 8C11: Lower limb mononeuropathy
Definition
Compressive neuropathy of the forefoot interdigital nerve chiefly due to compression and irritation at the plantar aspect of the transverse intermetatarsal ligament. It is not a true neuroma as the condition is degenerative rather than neoplastic. The most common location for Morton neuroma is between the 2nd and 3rd metatarsals.
Disease Hierarchy
DISIENZM: Neuroma
DISE0HPX: Morton neuroma
ICD Code
ICD-11
ICD-11: 8C11.6
ICD-10
ICD-10: G57.6
Expand ICD-11
'8C11.6
Expand ICD-10
'G57.6
Disease Identifiers
MONDO ID
MONDO_0700058
MESH ID
D000070607
UMLS CUI
C0311337
MedGen ID
90231
SNOMED CT ID
1.62E+16

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CNTX-4975 DMB4JPG Phase 3 NA [1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
GZMM OTEC5CWT Strong Biomarker [2]
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References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Radiographic Analysis of Feet With and Without Morton's Neuroma.Foot Ankle Int. 2017 Mar;38(3):310-317. doi: 10.1177/1071100716674998. Epub 2016 Nov 13.