Details of Disease

General Information of Disease (ID: DISF2AAW)

• Disease Name: Acute decompensated heart failure
• Disease Class: BD10-BD1Z: Heart failure
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISF2AAW: Acute decompensated heart failure
• ICD Code:
  ICD-11: ICD-11: BD1Z
  ICD-10: ICD-10: I50, I50.9
  ICD-9: ICD-9: 428
  Expand ICD-9: 428

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 6 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Subcutaneous furosemide	DMS49L2	Phase 2/3	NA	[1]
BMS-986231	DMITL03	Phase 2	NA	[2]
Cinaciguat	DMGEAM6	Phase 2	Small molecular drug	[3]
CXL-1020	DMENQ3Z	Phase 2	NA	[4]
RT-400	DM8DVC9	Phase 2	Peptide	[1]
SLV 306	DMCDON3	Phase 2	Small molecular drug	[5]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] ClinicalTrials.gov (NCT02157506) A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure. U.S. National Institutes of Health.
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5168).
• [4] ClinicalTrials.gov (NCT01096043) A Dose-Defining Study of CXL-1020 in Patients With Systolic Heart Failure. U.S. National Institutes of Health.
• [5] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6506).