Details of Disease | DrugMAP

General Information of Disease (ID: DISFCC43)

Disease Name	Patent ductus arteriosus 3
Synonyms	PDA3; patent ductus arteriosus 3; PRDM6 patent ductus arteriosus; patent ductus arteriosus caused by mutation in PRDM6
Definition	Any patent ductus arteriosus in which the cause of the disease is a mutation in the PRDM6 gene.
Disease Hierarchy	DIS9P8YS: Patent ductus arteriosus DISFCC43: Patent ductus arteriosus 3
Disease Identifiers	MONDO ID MONDO_0024266 UMLS CUI C4310753 OMIM ID 617039 MedGen ID 934720

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
PRDM6	OTKY12D9	Limited	Autosomal dominant	[1]
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References

1	Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. Am J Hum Genet. 2016 Jun 2;98(6):1082-1091. doi: 10.1016/j.ajhg.2016.03.022. Epub 2016 May 12.