Details of Disease | DrugMAP

General Information of Disease (ID: DISFLIBD)

Disease Name	Pancreatic cancer, susceptibility to, 3
Synonyms	Pnca3; susceptibility to pancreatic cancer 3; familial pancreatic carcinoma caused by mutation in PALB2; pancreatic cancer, susceptibility to, type 3; pancreatic cancer, susceptibility to, 3; PALB2 familial pancreatic carcinoma
Definition	Any familial pancreatic carcinoma in which the cause of the disease is a mutation in the PALB2 gene.
Disease Hierarchy	DISGXLG5: Hereditary neoplastic syndrome DISFLIBD: Pancreatic cancer, susceptibility to, 3
Disease Identifiers	MONDO ID MONDO_0013236 UMLS CUI C3150547 OMIM ID 613348 MedGen ID 461897

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
PALB2	OT6DNDBG	Strong	Autosomal dominant	[1]
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References

1	Current Approaches to Pancreatic Cancer Screening. Am J Pathol. 2019 Jan;189(1):22-35. doi: 10.1016/j.ajpath.2018.09.013.