Details of Disease

General Information of Disease (ID: DISFXBD4)

• Disease Name: Graft rejection in heart transplantation
• Disease Class: NE84: Transplant rejection
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISFXBD4: Graft rejection in heart transplantation
• ICD Code:
  ICD-11: ICD-11: NE84
  ICD-9: ICD-9: 996
  Expand ICD-9: 996

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Epratuzumab	DMI1ZXV	Phase 3	Antibody	[1]
Reparixin	DMVBA7I	Phase 3	Small molecular drug	[2]

This Disease is Treated as An Indication in 1 Preclinical Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
VT-111	DMOY15R	Preclinical	NA	[3]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8088).
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8498).
• [3] New developments in immunosuppressive therapy for heart transplantation. Expert Opin Emerg Drugs. 2009 Mar;14(1):1-21.