Details of Disease

General Information of Disease (ID: DISKOLA0)

Disease Name Immunodeficiency 83, susceptibility to viral infections
Synonyms IMD83
Definition An inherited susceptibility or predisposition to developing viral infections.
Disease Hierarchy
DISWHADJ: Encephalitis, acute, infection-induced, susceptibility to
DISKOLA0: Immunodeficiency 83, susceptibility to viral infections
Disease Identifiers
MONDO ID
MONDO_0800187
UMLS CUI
C2751803
OMIM ID
613002
MedGen ID
416638

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
TLR3 TTD24Y0 Limited Unknown [1]
TLR3 TTD24Y0 Strong Biomarker [2]
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This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
TLR3 OT8QPYXZ Limited Unknown [1]
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References

1 TLR3 deficiency in patients with herpes simplex encephalitis. Science. 2007 Sep 14;317(5844):1522-7. doi: 10.1126/science.1139522.
2 TLR3 Mutations in Adult Patients With Herpes Simplex Virus and Varicella-Zoster Virus Encephalitis.J Infect Dis. 2017 May 1;215(9):1430-1434. doi: 10.1093/infdis/jix166.