Details of Disease

General Information of Disease (ID: DISL46JF)

• Disease Name: Muscle atrophy
• Synonyms: wasting - muscle; muscle wasting; amyotrophia
• Disease Class: FB32-FB3Z: Muscle disorder
• Definition: The loss of muscle tissue due to inactivity or disease.
• Disease Hierarchy:
  DISOWG27: Myopathy
  DISL46JF: Muscle atrophy
• ICD Code:
  ICD-11: ICD-11: FB32.Y
  Expand ICD-11: 'FB32.Y
• Disease Identifiers:
  MONDO ID: MONDO_0004323
  MESH ID: D009133
  UMLS CUI: C0541794
  MedGen ID: 892680
  HPO ID: HP:0003202
  SNOMED CT ID: 88092000

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 6 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
BYM338	DM1ARHT	Phase 3	NA	[1]
GTx-024	DMZXF05	Phase 3	Small molecular drug	[2]
AMG 745	DMFXN2T	Phase 2	NA	[3]
CK-2127107	DM9FHV8	Phase 2	NA	[4]
SAR391786	DMS1YPZ	Phase 2	Antibody	[5]
PS-178990	DM2594H	Phase 1	NA	[6]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] ClinicalTrials.gov (NCT01355497) Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line Platinum. U.S. National Institutes of Health.
• [3] ClinicalTrials.gov (NCT00975104) AMG 745 in Subjects With Age-associated Muscle Loss. U.S. National Institutes of Health.
• [4] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037810)
• [5] ClinicalTrials.gov (NCT01963598) Study of the Safety and Efficacy of REGN1033 (SAR391786) in Patients With Sarcopenia. U.S. National Institutes of Health.
• [6] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027228)