Details of Disease | DrugMAP

General Information of Disease (ID: DISL7Q3J)

Disease Name	Obsolete glaucoma 1, open angle, E
Synonyms	chronic simple glaucoma
Definition	OBSOLETE. A form of glaucoma in which there is no visible abnormality in the trabecular meshwork.
Disease Hierarchy	DIS01GPL: Grass pollen hypersensitivity DISL7Q3J: Obsolete glaucoma 1, open angle, E

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CDKN2B	OTAG24N1	Limited	Autosomal dominant	[1]
OPTN	OT2UXWH9	Strong	Autosomal dominant	[2]
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References

1	Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
2	Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science. 2002 Feb 8;295(5557):1077-9. doi: 10.1126/science.1066901.