Details of Disease | DrugMAP

General Information of Disease (ID: DISN7E8S)

Disease Name	Dilated cardiomyopathy 1JJ
Synonyms	cardiomyopathy, dilated, 1JJ; LAMA4 familial isolated dilated cardiomyopathy; cardiomyopathy, dilated, type 1Jj; familial isolated dilated cardiomyopathy caused by mutation in LAMA4; dilated cardiomyopathy type 1JJ; CMD1JJ
Definition	Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the LAMA4 gene.
Disease Hierarchy	DISBHDU9: Familial dilated cardiomyopathy DISN7E8S: Dilated cardiomyopathy 1JJ
Disease Identifiers	MONDO ID MONDO_0014095 UMLS CUI C3808935 OMIM ID 615235 MedGen ID 815265

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
LAMA4	OTHI7TA0	Strong	Autosomal dominant	[1]
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References

1	Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells. Circulation. 2007 Jul 31;116(5):515-25. doi: 10.1161/CIRCULATIONAHA.107.689984. Epub 2007 Jul 23.