Details of Disease | DrugMAP

General Information of Disease (ID: DISNMINM)

Disease Name	Intellectual disability, X-linked 105
Synonyms	mental retardation, X-linked 105; intellectual disability, X-linked 105; intellectual developmental disorder, X-linked 105, X-linked recessive; MRX105; USP27X non-syndromic X-linked intellectual disability; non-syndromic X-linked intellectual disability caused by mutation in USP27X; intellectual disability, X-linked type 105; mental retardation, X-linked type 105
Definition	Any non-syndromic X-linked intellectual disability in which the cause of the disease is a mutation in the USP27X gene.
Disease Hierarchy	DIS71AI3: Non-syndromic X-linked intellectual disability DISNMINM: Intellectual disability, X-linked 105
Disease Identifiers	MONDO ID MONDO_0010510 UMLS CUI C4310816 OMIM ID 300984 MedGen ID 934783

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
USP27X	OT9LZUX6	Strong	X-linked	[1]
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References

1	X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes. Mol Psychiatry. 2016 Jan;21(1):133-48. doi: 10.1038/mp.2014.193. Epub 2015 Feb 3.