Details of Disease

General Information of Disease (ID: DISOX2NY)

Disease Name Pneumocystis infectious disease
Synonyms infections, Pneumocystis; Pneumocystis infection
Definition
Infections with species in the genus pneumocystis, a fungus causing interstitial plasma cell pneumonia (pneumonia, pneumocystis) and other infections in humans and other mammals. Immunocompromised patients, especially those with aids, are particularly susceptible to these infections. Extrapulmonary sites are rare but seen occasionally.
Disease Hierarchy
DIS9K7PB: Mycoses
DISEM33Q: Infectious disease
DISOX2NY: Pneumocystis infectious disease
Disease Identifiers
MONDO ID
MONDO_0005923
MESH ID
D016720
UMLS CUI
C0851886
MedGen ID
163415

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
HLA-DRB1 TTUXSTW Strong Biomarker [1]
PRCP TTTJZ4M Strong Biomarker [2]
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References

1 Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages.BMC Microbiol. 2010 Apr 8;10:103. doi: 10.1186/1471-2180-10-103.
2 Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species.Infect Immun. 2004 Oct;72(10):6002-11. doi: 10.1128/IAI.72.10.6002-6011.2004.